Sodium Fluoride does not Alter Sperm Production or Sperm Morphology in Rats
نویسندگان
چکیده
The aim of the present study was to evaluate the effects of sodium fluoride (NaF) on the male reproductive system. Adult male rats were exposed to NaF in drinking water for 30 days at three concentrations: 1.54 (control, tap water), 50 and 100 ppm. Body and organ weights, daily sperm production, sperm number and morphology were investigated. No difference was observed on the sperm number and morphology among the groups, as well as body weight and organ absolute and relative weights. Overall, despite the presence of a mild degree of dental fluorosis in the higher dose group, the results indicated that exposure to NaF at the doses used in the present study did not adversely affect sperm production and morphology of male rats.
منابع مشابه
Protective effects of vitamin E and selenium on spermatogenesis in adult male rat insulin-resistant
Background & Objective: Diabetes mellitus is a metabolic disease and is a multifactorial disorder characterized by chronic hyperglycemia resulting from impaired insulin secretion and insulin factional or both. In this study, the protective role of vitamin E and sodium selenite in preventing the harmful effects of insulin resistance (diabetes type 2) on spermatogenesis was studied. Materials &...
متن کاملEffect of vitamin E on sperm parameters and DNA integrity in sodium arsenite-treated rats
BACKGROUND Arsenic as an environmental toxicant is able to exert malformations in male reproductive system by inducing oxidative stress. Vitamin E (Vit.E) is known as antioxidant vitamin. OBJECTIVE The aim of this study was to investigate the harmful effects of sodium arsenite on sperm parameters and the antioxidant effects of Vit.E on sperm anomalies in sodium arsenite treated rats. MATERI...
متن کاملEffects of ganoderma lucidum and melatonin on sperm in rats exposed to electromagnetic field
Background: The aim of this study was to investigate the effect of the electromagnetic field (EMF) generated by 10 kV (50 Hz) high voltage line on the epididymal sperm characteristics and the protective effects of ganoderma lucidum (GL) and melatonin (M) in EMF exposed male rats. Materials and Methods: In this study, 64 Wistar rats were divided into 8 groups (n= 8). Rats in 26-day and 52-day ex...
متن کاملP-19: Association of Poor Chromatin Remodeling with Cytosolic ROS and Mitochondrial ROS in Sperm of Infertile Men
Background: Cytoplasm and mitochondria are considered as the major origins of sperm ROS production. Sperm is prone to DNA damage by exposure to ROS or due impaired chromatin remodeling or low DNA protamination. Therefore, the aim of this study was to see if there is any association between impaired chromatin packaging and origin of ROS production. Materials and Methods: Cytosolic ROS, mitochond...
متن کاملO-3: Does Antioxidant Therapy Adds any Benefit in Improvement of Sperm Parameters to Standard Inguinal Varicocelectomy? A Randomize Case-Control Study
Background: Varicocele occurs in approximately 15 to 20% of the general male population and it is the most common cause of poor semen production and decreased semen quality. Clinical studies have show that varicocele surgery can improve semen quality. The aim of this study was to evaluate if antioxidant therapy adds any extra benefit to standard inguinal varicocelectomy in improvement of sperm ...
متن کامل